structure-baseddrugdesign相关论文
Discovery of etravirine-JLJ506 hybrids as potent HIV-1 NNRTIs through structure-guided molecular hyb
The long-term usage of HIV-1 non-nucleoside reverse transcriptase inhibitors(NNRTIs)usually leads to rapid emergence of ......
This study was designed to develop hypothetical inhibition mechanism of novel UTB inhibitor and exploit novel compounds ......
Structure-based drug discovery and design for novel small molecular inhibitors of Sphingomyelin synt
Aim To discover novel small molecular inhibitors of sphingomyelin synthase(SMS)as a tool to study the biological functio......
Structure-Based Design and Synthesis of Novel Propane-1,3-diamino Bridged Derivatives as C-C Chemoki
Preventing of HIV entry into human host cells is an attractive way to controlling viral infection and replication,CCR5 i......
Urea transporter B (UT-B) is a membrane protein extensively expressed in various tissues, such as kidney, testis, brain,......
Urea transporter B (UT-B) is a membrane channel protein that specifically transports urea.UT-B null mouse exhibited urea......
Molecular Basis of the Interaction for an Essential Subunit PA-PB1 in Influenza Virus RNA Polymerase
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SM02-P07:Synthesis and biological evaluation of novel pyrrolidine derivatives as influenza neuramini
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Discovery of Novel Antibacterial Agents by Structure-based Drug Design, Synthesis and Biological Eva
The emergence and spread of antibiotic resistance represent a severe global issue.New drug targets and novel lead co......
VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) plays an essential role in the signal transduction pathway of......
